H1-4 Gene:H1-4 is a single-exon and small gene, encodes the H1.4 linker histone that is a basic unit of chromosome.
H1-4Mutations:To date, all reported H1-4pathogenic mutations are missing 1 to 5 base pairs of DNA at the end of H1-4gene.
Mechanism of disease causation: Mutant H1-4 protein is stable and is believed to disrupt the normal function of chromatin.
H1-4