Families

PTEN-related disease, called PHTS for PTENHamartoma Tumor Syndrome, is a genetic condition that can affect many parts of the body. Medical concerns differ depending on the patient’s age and sex. In children, learning difficulties and schooling may be an issue, whereas in adults, the risk of cancer becomes the main concern.

The condition is inherited in an autosomal dominant way, which means that one changed copy of the gene is enough to cause the disorder. Some people inherit the change from a parent, while others have a new gene variation.