LAMC3is a gene that gives the body instructions to make part of a protein called laminin, which helps cells communicate, move, and organize during development. In the developing brain, LAMC3appears to help the brain surface form and fold correctly. Most affected individuals reported so far have changes in both copies of the LAMC3gene. These changes may stop the gene from working properly, leading to differences in brain development. Genetic testing, often using a gene panel or exome sequencing, can identify changes in LAMC3and help confirm the diagnosis.
LAMC3