This website provides information on xeroderma pigmentosum (XP) patients with mutations in the XPF/ERCC4 gene, including clinical data, molecular data, management and research options.
The syndrome, caused by mutations in the XPFgene, is a disorder characterized by sunburn sensitivity, skin pigmentation changes, neurological degeneration.
Not all individuals with a mutation in the XPFgene have these features.
This website was created to share and collect information about clinic, management and research projects to gather more knowledge and provide better treatment of patients with mutations in the XPFgene.
Professor Alan Lehmann, University of Sussex, Brighton, UK, a.r.lehmann@sussex.ac.uk
XPF